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Mechanism of action of Lyrica (50, 75, 100, 150 and 300)mg:
Lyrica contain the active medicament known as Pregabalin is chemically interrelated to Gabapentin. The mechanism of action of Pregabalin is still not clear. Pregabalin acts on the calcium channels present on neurons and modify the release of neurotransmitters and thus the communication between nerves gets reduced. It decreases the pain and seizures.
Lyrica is a remarkable orally administered medication, which is particularly meant for treating nerve pain or neuropathic pain in those individuals who are facing diabetic neuropathy pain. Generic Pregabalin is a main remedial constituent found in Lyrica, which belongs to the group of medications known as Anti-convulsant drugs. Generic Pregabalin directly works on the neurotransmitter chemicals, which are responsible for causing pain and convulsions.
Apart from treating nerve pain, Lyrica is also used for treating epileptic seizures.
Conditions in which the use of Lyrica 150 mg is contraindicated-
The Lyrica drug is contraindicated in following conditions:
Congestive heart failure.
Bleeding disorder and low platelets count in your blood.
If a patient has a history depression or suicidal tendency.
If a patient is hypersensitive to Lyrica or its other ingredients.
Doses of Lyrica-
Lyrica is accessible into the capsule dosage form and its presented strengths are 50mg, 75mg, 100mg, 150, 200mg and 300mg. The dose of Lyrica medication totally depends on individual’s age, body weight, and severity of diseased condition.
For neuropathic pain- one capsule of Lyrica 50mg orally three times a day via oral route with plenty of water. The dose may be increased up to 300mg within one week.
For Postherpetic Neuralgia: The recommended dose of Lyrica is 75 mg to 150 mg orally two times in a day.
For Fibromyalgia: 50 mg of Lyrica should be administered by mouth three times a day and the maximum prescribed dose of Lyrica is 225mg within a single day.
For partial seizures- The suggested dose of Lyrica is 150 to 600mg/day in the form of adjunctive therapy for managing partial onset seizures in adults.
Drug Interactions of Lyrica (50, 75, 100, 150 and 300)mg-
Lyrica shows some drug interaction with other drugs when administered together :
Antihistamines: Cetirizine, Diphenhydramine
Drugs for anxiety: Alprazolam, Diazepam, Zolpidem
Narcotic drug: Coedine
Anti-diabetic medicines: Rosiglitazone, Pioglitazone
Storage condition for Lyrica 150 mg-
Paraflex should be stored at room temperature. It should kept away from heat, light and moisture. Keep this medicine out reach of children and pets.
Take the dose as soon as you remember it, skip the missed dose in case if it is the time for next dose.
What happens in case of overdosing of medicine?
In case of overdose of this medicine, consult your doctor op local emergency service as soon as possible.
What are the side effects of Lyrica?
The most common undesired effects produced while using Lyrica are anxiety, dizziness, somnolence, dry mouth, constipation, nausea, edema, blurred vision, weight gain and thinking abnormal.
What are the safety measures taken while using Lyrica?
Don't use this medicine without sedative drug because it may potentiate the sedative action.
Use this medicine with caution in case if you have cardiovascular disease.
Don't discontinue anticonvulsant suddenly because it may elevate seizure frequency.
Don't drive a car or perform hazardous work after taking this medicine.
It increases the risk of suicidal thoughts, so always monitor your activity.
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